BOIL Biomedical Optics and Imaging Lab

Publications

Selected publications

A selection of recent and representative work, grouped by subject. The complete and continuously updated record, including conference proceedings and preprints, is on Google Scholar.

Full record on Google Scholar

Neuromonitoring and cerebral blood flow

  1. Moore CH, Wayne MA, Ulku AC, Mos P, Bruschini C, Charbon E, Sunar U. Characterization of a fiber-coupled SPAD camera system for deep-tissue blood-flow measurement using diffuse correlation spectroscopy. Biomedical Optics Express, 2026, 17(4). doi.org/10.1364/BOE.588814
  2. Azizi Zade F, Dar I, Foreman B, Sunar U. Binary Classification of Consciousness Using Cerebral Blood Flow and EEG Features. Neurocritical Care, 2026. doi.org/10.1007/s12028-026-02603-2
  3. Poon CS, Langri DS, Rinehart B, Rambo TM, Miller AJ, Foreman B, Sunar U. First-in-clinical application of a time-gated diffuse correlation spectroscopy system at 1064 nm using superconducting nanowire single photon detectors in a neuro intensive care unit. Biomedical Optics Express, 2022, 13(3), 1344. doi.org/10.1364/BOE.448135
  4. Moore CH, Sunar U, Lin W. A Device-on-Chip Solution for Real-Time Diffuse Correlation Spectroscopy Using FPGA. Biosensors, 2024, 14(8), 384. doi.org/10.3390/bios14080384
  5. Langri DS, Sunar U. Non-Invasive Continuous Optical Monitoring of Cerebral Blood Flow after Traumatic Brain Injury in Mice Using Fiber Camera-Based Speckle Contrast Optical Spectroscopy. Brain Sciences, 2023, 13(10), 1365. doi.org/10.3390/brainsci13101365
  6. Li J, Poon CS, Kress J, Rohrbach DJ, Sunar U. Resting-state functional connectivity measured by diffuse correlation spectroscopy. Journal of Biophotonics, 2017. doi.org/10.1002/jbio.201700165

Cancer imaging and imaging-guided therapy

  1. Kluiszo E, Ahmmed R, Aliu B, Aygun-Sunar S, Willadsen M, Kutscher HL, Lovell JF, Sunar U. Mesoscopic Fluorescence Imaging of Light-Triggered Chemotherapeutic Release in Cancer Spheroid Models. Pharmaceutics, 2026, 18(4), 495. doi.org/10.3390/pharmaceutics18040495
  2. Ahmmed R, Kluiszo E, Aygun-Sunar S, Willadsen M, Kutscher HL, Lovell JF, Sunar U. Quantitative Fluorescence Imaging of Chemophototherapy Drug Pharmacokinetics Using Laparoscopic SFDI. International Journal of Molecular Sciences, 2025, 26(12), 5571. doi.org/10.3390/ijms26125571
  3. Rohrbach DJ, Carter KA, Luo D, Shao S, Aygun-Sunar S, Lovell JF, Sunar U. Fluence Rate-Dependent Kinetics of Light-Triggered Liposomal Doxorubicin Assessed by Quantitative Fluorescence-Based Endoscopic Probe. International Journal of Molecular Sciences, 2025, 26(3), 1212. doi.org/10.3390/ijms26031212
  4. Chitgupi U, Qin Y, Ghosh S, Quinn B, Carter K, He X, Sunar U, Lovell JF. Folate-Targeted Nanoliposomal Chemophototherapy. Pharmaceutics, 2023, 15(10), 2385. doi.org/10.3390/pharmaceutics15102385
  5. Kress J, Rohrbach DJ, Carter KA, Luo D, Poon C, Aygun-Sunar S, Shao S, Lele S, Lovell JF, Sunar U. A dual-channel endoscope for quantitative imaging, monitoring, and triggering of doxorubicin release from liposomes in living mice. Scientific Reports, 2017, 7(1), 15578. doi.org/10.1038/s41598-017-15790-y

Tissue characterization and dosimetry

  1. Zhu TC, Pogue BW, Dimofte A, Finlay JC, Lilge L, Sunar U, Simone CB, van Veen RLP. AAPM Task Group Report 274: Fluence rate dosimetry for photodynamic therapy (PDT). Medical Physics, 2025, 52(3). doi.org/10.1002/mp.17613
  2. Travers JB, Poon C, Rohrbach DJ, Weir NM, Cates E, Hager F, Sunar U. Noninvasive mesoscopic imaging of actinic skin damage using spatial frequency domain imaging. Biomedical Optics Express, 2017, 8(6). doi.org/10.1364/BOE.8.003045